BDBM50335570 CHEMBL1650844::{1-[4-(2-{Hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1Hbenzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol

SMILES OCC1(CCCCCCC1)N1CCC(CC1)n1c(nc2ccccc12)N1CC2CNCC2C1

InChI Key InChIKey=MEBYDATXPNEUSM-UHFFFAOYSA-N

Data  5 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50335570   

TargetNociceptin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335570(CHEMBL1650844 | {1-[4-(2-{Hexahydropyrrolo[3,4-c]p...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cells after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335570(CHEMBL1650844 | {1-[4-(2-{Hexahydropyrrolo[3,4-c]p...)
Affinity DataKi:  201nMAssay Description:Displacement of [3H]DAMGO from human MOP receptor expressed in CHO-K1 cells after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335570(CHEMBL1650844 | {1-[4-(2-{Hexahydropyrrolo[3,4-c]p...)
Affinity DataKi: >577nMAssay Description:Displacement of [3H]enadoline from human KOP receptor expressed in HEK-293 cells after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335570(CHEMBL1650844 | {1-[4-(2-{Hexahydropyrrolo[3,4-c]p...)
Affinity DataKi:  3.70E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335570(CHEMBL1650844 | {1-[4-(2-{Hexahydropyrrolo[3,4-c]p...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]DPDPE from human DOP receptor expressed in CHO-K1 cells after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335570(CHEMBL1650844 | {1-[4-(2-{Hexahydropyrrolo[3,4-c]p...)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at human MOP receptor expressed in CHO-K1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by liquid scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335570(CHEMBL1650844 | {1-[4-(2-{Hexahydropyrrolo[3,4-c]p...)
Affinity DataEC50:  12nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cells after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed