BDBM50335951 2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-methoxy-4'-(1-methyl-1H-pyrazol-4-yl)biphenyl-3-yl)acetic acid::CHEMBL1668895

SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)-c1cnn(C)c1)C(=O)C1CC1

InChI Key InChIKey=RPYZMEMQTMVNLG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50335951   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335951(2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-m...)
Affinity DataIC50:  27nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335951(2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-m...)
Affinity DataIC50:  4nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape change by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335951(2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-m...)
Affinity DataIC50:  37nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation counting in presence of 0.2 % HSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed