BDBM50338500 (S)-1-((1-benzyl-1H-1,2,3-triazol-5-yl)methyl)-5-((2-(methoxymethyl)pyrrolidin-1-yl)sulfonyl)indoline-2,3-dione::CHEMBL1683316

SMILES COC[C@@H]1CCCN1S(=O)(=O)c1ccc2N(Cc3cnnn3Cc3ccccc3)C(=O)C(=O)c2c1

InChI Key InChIKey=LTPNBPPPHHCVFP-SFHVURJKSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50338500   

TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM50338500((S)-1-((1-benzyl-1H-1,2,3-triazol-5-yl)methyl)-5-(...)
Affinity DataKi:  10.5nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Oslo

Curated by ChEMBL
LigandPNGBDBM50338500((S)-1-((1-benzyl-1H-1,2,3-triazol-5-yl)methyl)-5-(...)
Affinity DataIC50:  9nMAssay Description:Inhibition of caspase 3 using Ac-DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed