BDBM50341377 3-(2-chlorophenyl)-7-[(trans-4-hydroxycyclohexyl)amino]-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one::CHEMBL1235713::trans-3-(2-chlorophenyl)-7-(4-hydroxycyclohexylamino)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one

SMILES O[C@H]1CC[C@@H](CC1)Nc1ncc2CN(C(=O)Nc2n1)c1ccccc1Cl

InChI Key InChIKey=NSHBSERFNQQOCC-JOCQHMNTSA-N

Data  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341377   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50341377(3-(2-chlorophenyl)-7-[(trans-4-hydroxycyclohexyl)a...)
Affinity DataKd:  32nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50341377(3-(2-chlorophenyl)-7-[(trans-4-hydroxycyclohexyl)a...)
Affinity DataKd: >2.00E+4nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed