BDBM50350235 CHEMBL1812334

SMILES N[C@H](Cc1cccc(Cl)c1)C(=O)N1CCN(CC1)C(=O)c1cc(F)ccc1F

InChI Key InChIKey=NASCAWUSOSJBJH-GOSISDBHSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50350235   

TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50350235(CHEMBL1812334)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human HDAC1 using rhodamine as substrate after 1 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50350235(CHEMBL1812334)
Affinity DataIC50:  200nMAssay Description:Inhibition of N terminal hexahistidine-tagged human HDAC8 expressed in Sf9 cells after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50350235(CHEMBL1812334)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human HDAC6 using rhodamine as substrate after 1 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50350235(CHEMBL1812334)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human HDAC2 using rhodamine as substrate after 1 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed