BDBM50377847 CHEMBL413999

SMILES CN(C)c1cccc(CNC[C@@H](O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CN(Cc3cc(F)cc(F)c3)C(=O)N2)c1

InChI Key InChIKey=WUINFQUMQLJWPY-HZFUHODCSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50377847   

TargetBeta-secretase 1(Homo sapiens (Human))
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50377847(CHEMBL413999)
Affinity DataKi:  53nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50377847(CHEMBL413999)
Affinity DataKi:  417nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50377847(CHEMBL413999)
Affinity DataIC50:  1.97E+3nMAssay Description:Inhibition of human BACE1 by SEAP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed