BDBM50379147 CHEMBL2012830::US8703811, 49
SMILES CCc1nc2ccccc2n1-c1ccc(s1)C(=O)NC1CC1
InChI Key InChIKey=MJCLATPPZLJYPG-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50379147
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human DHODH after 20 mins by 2,6-dichloroindophenol-reduction based assayMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. falciparum)
Genzyme
US Patent
Genzyme
US Patent
Affinity DataIC50: 113nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair