BDBM50381091 CHEMBL2017555

SMILES CCC(O)(CC)c1ccc2c(c([nH]c2c1)-c1n[nH]c2ccsc12)-c1ccc(OC)cc1

InChI Key InChIKey=LXMWGYNOGUKODT-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50381091   

TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381091(CHEMBL2017555)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Itk (357-620) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation coun...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381091(CHEMBL2017555)
Affinity DataIC50:  241nMAssay Description:Inhibition of Txk autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381091(CHEMBL2017555)
Affinity DataIC50:  3.18E+3nMAssay Description:Inhibition of Lck autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381091(CHEMBL2017555)
Affinity DataIC50:  939nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Syk (343 to 635) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed