BDBM50387418 CHEMBL2047245
SMILES CC(C)c1ccc(Nc2[nH]c(N)nc3cc4ccccc4c23)cc1
InChI Key InChIKey=KYAAXSDBTAUNKQ-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50387418
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of PDGFRbeta in human SF539 cells pretreated for 60 mins measured after 1 hr by ELISAMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of VEGFR2 in human U251 cells pretreated for 60 mins measured after 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 4.26E+4nMAssay Description:Inhibition of EGFR in human A431 cells pretreated for 60 mins measured after 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: >1.60E+4nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: >1.40E+4nMAssay Description:Inhibition of human thymidylate synthaseMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: >1.40E+4nMAssay Description:Inhibition of Toxoplasma gondii thymidylate synthaseMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: >1.60E+4nMAssay Description:Inhibition of Toxoplasma gondii DHFRMore data for this Ligand-Target Pair