BDBM50387545 CHEMBL2059907
SMILES CC(=O)Nc1nc2ccc(cn2n1)-c1cncc(c1)S(C)(=O)=O
InChI Key InChIKey=RCRCKEODQLBHAY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50387545
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: 79.4nMAssay Description:Inhibition of PI3Kgamma by high throughput chemoproteomics binding assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of PI3Kdelta by high throughput chemoproteomics binding assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: >6.31E+4nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of C5a-induced AKT phosphorylation at Ser473 by cell based assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: 79.4nMAssay Description:Inhibition of PI3Kgamma in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of fMLP-induced neutrophil migration assay by cell based assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of PI3Kdelta in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of PI3Kalpha in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of PI3Kalpha by high throughput chemoproteomics binding assayMore data for this Ligand-Target Pair