BDBM50390071 CHEMBL2069411

SMILES OCc1ccc(cn1)-c1cccc2OC[C@H](Cc12)NC(=O)c1ccc(OCC(F)(F)F)nc1

InChI Key InChIKey=DXYBEOOKXLMROC-KRWDZBQOSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50390071   

TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50390071(CHEMBL2069411)
Affinity DataIC50:  200nMAssay Description:Displacement of [125I]ghrelin from GHS receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50390071(CHEMBL2069411)
Affinity DataIC50:  158nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by whole-cell voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50390071(CHEMBL2069411)
Affinity DataIC50:  2.00E+3nMAssay Description:Displacement of [125I]RTI-55 from DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50390071(CHEMBL2069411)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by IonWorks HT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50390071(CHEMBL2069411)
Affinity DataIC50:  6.31E+3nMAssay Description:Inhibition of human NaV1.5 expressed in CHO cells by IonWorks assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed