BDBM50390795 CHEMBL2070619

SMILES COc1cc(Cl)c(c(Cl)c1)-c1cc(nc(n1)-c1cnccn1)-c1cnc(NC(C)=O)s1

InChI Key InChIKey=XACSASLXEAYEEO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50390795   

TargetLIM domain kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50390795(CHEMBL2070619)
Affinity DataIC50:  30nMAssay Description:Inhibition of LIMK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50390795(CHEMBL2070619)
Affinity DataIC50:  8nMAssay Description:Inhibition of LIMK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50390795(CHEMBL2070619)
Affinity DataIC50:  8nMAssay Description:Inhibition of human LIMK1 (312 to 638 residues) expressed in Sf9 cells using dextrin as substrate incubated for 30 mins by micro-scintillation fluid ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity testis-specific protein kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50390795(CHEMBL2070619)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of TESK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50390795(CHEMBL2070619)
Affinity DataIC50:  30nMAssay Description:Inhibition of human LIMK1 (321 to 647 residues) expressed in Sf9 cells using dextrin as substrate incubated for 30 mins by micro-scintillation fluid ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity testis-specific protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50390795(CHEMBL2070619)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of TESK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed