BDBM50391936 CHEMBL2147758

SMILES Oc1ccc2C(=O)\C(Oc2c1CN1CCCCCC1)=C\c1c[nH]c2ccccc12

InChI Key InChIKey=IARYZBOIUVHJGF-XKZIYDEJSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50391936   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))TBA
LigandPNGBDBM50391936(CHEMBL2147758)
Affinity DataIC50:  4.10E+5nMAssay Description:Inhibition of full length human PIM1 expressed in Escherichia coli BL21 (DE3) preincubated for 0.5 hrs followed by substrate addition and measured af...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))TBA
LigandPNGBDBM50391936(CHEMBL2147758)
Affinity DataIC50:  410nMAssay Description:Inhibition of PIM1 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed