BDBM50393115 CHEMBL575945

SMILES Nc1nc2c(nccc2[nH]1)-c1c[nH]c2ccccc12

InChI Key InChIKey=VDQPKRPHLSTBEH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50393115   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Macquarie University

Curated by ChEMBL
LigandPNGBDBM50393115(CHEMBL575945)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human recombinant PIM1 using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Macquarie University

Curated by ChEMBL
LigandPNGBDBM50393115(CHEMBL575945)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of MMP14 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by fluorescence ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50393115(CHEMBL575945)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed