BDBM50393332 CHEMBL2152125

SMILES CNC(=O)c1nc(cnc1N)-c1cccc(c1)-c1nnn[nH]1

InChI Key InChIKey=PLUDSXLHMVRUKP-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50393332   

LigandPNGBDBM50393332(CHEMBL2152125)
Affinity DataIC50:  21nMAssay Description:Inhibition of human PI3Kgamma expressed in sf9 cells assessed as amount of ATP consumed by luciferase-luciferin chemiluminescence assayMore data for this Ligand-Target Pair
LigandPNGBDBM50393332(CHEMBL2152125)
Affinity DataIC50:  529nMAssay Description:Inhibition of human PI3Kalpha expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50393332(CHEMBL2152125)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PI3Kgamma expressed in C5a-stimulated mouse RAW 264.7 cells assessed as inhibition of AKT phosphorylation by ELISAMore data for this Ligand-Target Pair
LigandPNGBDBM50393332(CHEMBL2152125)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of human PI3Kdelta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50393332(CHEMBL2152125)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of human PI3Kbeta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed