BDBM50394745 CHEMBL2165821

SMILES CCN(C)CCN1CCCc2cc(NC(=N)c3cccs3)ccc12

InChI Key InChIKey=GDMWZTBOBNMXTL-UHFFFAOYSA-N

Data  3 IC50  1 EC50

PDB links: 2 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50394745   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50394745(CHEMBL2165821)
Affinity DataEC50:  4.50E+3nMAssay Description:Inhibition of human ERG expressed in HEK293 cells at -80 mV holding potential assessed as reduction in tail current amplitude by conventional patch c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50394745(CHEMBL2165821)
Affinity DataIC50:  97nMAssay Description:Inhibition of human nNOS expressed in Sf9 cells assessed as reduction in conversion of [3H]L-arginine to [3H]L-citrulline preincubated for 15 mins by...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50394745(CHEMBL2165821)
Affinity DataIC50:  3.33E+4nMAssay Description:Inhibition of human eNOS expressed in Sf9 cells assessed as reduction in conversion of [3H]L-arginine to [3H]L-citrulline preincubated for 15 mins by...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50394745(CHEMBL2165821)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant iNOS expressed in Sf9 cells assessed as reduction in conversion of [3H]L-arginine to [3H]L-citrulline preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed