BDBM50398333 CHEMBL2178579

SMILES Oc1c(NC(=O)Nc2cccc(F)c2Cl)ccc(Cl)c1S(=O)(=O)N1CCNCC1

InChI Key InChIKey=YQYFEGTYCUQBEI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50398333   

TargetC-X-C chemokine receptor type 2(Human)
National Heart and Lung Institute

Curated by ChEMBL
LigandPNGBDBM50398333(CHEMBL2178579)
Affinity DataIC50: 5.10nMAssay Description:Binding affinity to CXCR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
National Heart and Lung Institute

Curated by ChEMBL
LigandPNGBDBM50398333(CHEMBL2178579)
Affinity DataIC50: 261nMAssay Description:Antagonist activity at CXCR2 assessed as inhibition of neutrophil CD11b up-regulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
National Heart and Lung Institute

Curated by ChEMBL
LigandPNGBDBM50398333(CHEMBL2178579)
Affinity DataIC50: 311nMAssay Description:Antagonist activity at CXCR2 assessed as inhibition of neutrophil shape changeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
National Heart and Lung Institute

Curated by ChEMBL
LigandPNGBDBM50398333(CHEMBL2178579)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to CXCR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed