BDBM50398374 CHEMBL2177376

SMILES C[C@@H]1C[C@@H](O)c2ncnc(N3CCN(CC3)C(=O)[C@H](CNCC(F)(F)F)c3ccc(Cl)cc3)c12

InChI Key InChIKey=RERSEUJKWZVXCS-ZTFGCOKTSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50398374   

TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50398374(CHEMBL2177376)
Affinity DataIC50:  2.01E+3nMAssay Description:Competitive inhibition of wild-type full-length amino-terminal polyhistidine-tagged human Akt2 expressed in recombinant baculovirus system using fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50398374(CHEMBL2177376)
Affinity DataIC50:  798nMAssay Description:Competitive inhibition of wild-type full-length amino-terminal polyhistidine-tagged human Akt3 expressed in recombinant baculovirus system using fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50398374(CHEMBL2177376)
Affinity DataIC50:  902nMAssay Description:Competitive inhibition of wild-type full-length amino-terminal polyhistidine-tagged human Akt1 expressed in recombinant baculovirus system using fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed