BDBM50401026 CHEMBL2204367

SMILES CC(C)[C@@H](C)NC(=O)c1cc(cc(n1)C(=O)NCCc1ccccn1)-c1cc2ccccc2n1C

InChI Key InChIKey=NQCIABFWMPKOJV-LJQANCHMSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50401026   

TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50401026(CHEMBL2204367)
Affinity DataKd:  656nMAssay Description:Binding affinity at human recombinant STAT6 by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50401026(CHEMBL2204367)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human STAT6 expressed in 293-EBNA cells assessed as inhibition of IL4-induced STAT6 transcriptional activation after 1 hr by Photinus p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and transcription activator 6(Mus musculus)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50401026(CHEMBL2204367)
Affinity DataIC50:  2.74E+3nMAssay Description:Inhibition of mouse STAT6 expressed in BEAS2B cells assessed as IL4-induced eotaxin-3 secretion after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed