BDBM50403757 CHEMBL1709089

SMILES CN1CC[C@@H]([C@@H](O)C1)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl

InChI Key InChIKey=BIIVYFLTOXDAOV-SJCJKPOMSA-N

Data  2 IC50

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50403757   

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Mitotix

Curated by ChEMBL

LigandBDBM50403757(CHEMBL1709089)Copy SMILESCopy InChI

Affinity DataIC50:  4.90E+4nMAssay Description:Inhibitory activity against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Mitotix

Curated by ChEMBL

LigandBDBM50403757(CHEMBL1709089)Copy SMILESCopy InChI

Affinity DataIC50:  5.60E+4nMAssay Description:Inhibitory activity against cyclin-dependent kinase 4-cyclin D1More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI