BDBM50409097 CHEMBL108697
SMILES Cc1c(C)c(=O)oc2cc(OCc3cccc(F)c3)ccc12
InChI Key InChIKey=XGJZBERLEOSMIT-UHFFFAOYSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50409097
Affinity DataIC50: 2.80nMAssay Description:Inhibitory activity against monoamine oxidase BMore data for this Ligand-Target Pair
Affinity DataIC50: 575nMAssay Description:Inhibitory activity against monoamine oxidase AMore data for this Ligand-Target Pair
Affinity DataIC50: 2.82nMAssay Description:Inhibitory effect on Monoamine oxidase B, SD on IC50 values < 10%More data for this Ligand-Target Pair
Affinity DataIC50: 575nMAssay Description:Inhibitory effect on monoamine oxidase A, SD on IC50 values < 10%More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Geneva
Curated by ChEMBL
University Of Geneva
Curated by ChEMBL
Affinity DataIC50: 0.912nMAssay Description:Inhibition of human supersomes MAOBMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine chloride as substrate incubated for 5 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of rat brain mitochondrial MAOB using kynuramine as substrate assessed as decrease in 4-hydroxyquinoline production by spectrophotometryMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Geneva
Curated by ChEMBL
University Of Geneva
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human MAO-B using p-tyramine as substrate assessed as decrease in H2O2 production incubated for 15 mins by fluorimetric met...More data for this Ligand-Target Pair
Affinity DataIC50: 575nMAssay Description:Inhibition of rat brain mitochondrial MAOA using kynuramine as substrate assessed as decrease in 4-hydroxyquinoline production by spectrophotometryMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human MAO-A using p-tyramine as substrate assessed as decrease in H2O2 production incubated for 15 mins by fluorimetric met...More data for this Ligand-Target Pair
Affinity DataIC50: 2.82nMAssay Description:Inhibition of rat brain MAOBMore data for this Ligand-Target Pair