BDBM50420775 CHEMBL581146::TCMDC-125324
SMILES Oc1c(cc(Cl)c2cccnc12)C(Nc1ccccn1)c1ccco1
InChI Key InChIKey=SZEZEZHDZJZXEC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50420775
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Pennsylvania
Curated by ChEMBL
University Of Pennsylvania
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Eutropics Pharmaceuticals
Curated by ChEMBL
Eutropics Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of human GST-tagged Mcl1 expressed in Escherichia coli BL21 using FITC-AHA-MRPEIWIAQELRRIGDEFNA-[NH2] after 20 mins by fluorescence polari...More data for this Ligand-Target Pair