BDBM50425314 CHEMBL2315877
SMILES Clc1ccc2oc(nc2c1)N1CCC(CC1)C(=O)NC1CCCC1
InChI Key InChIKey=RHVOATXSWKOVKB-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50425314
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX2 in human fetal fibroblast assessed as SnCl2-induced PGF2alpha production after 40 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 850nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 853nMAssay Description:Inhibition of human recombinant mPGES-1 using PGH2 as substrate incubated 20 mins prior to substrate addition measured after 30 secs by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of COX2 in human fetal fibroblast assessed as inhibition of IL-1beta-mediated PGE2 production after 50 mins by ELISAMore data for this Ligand-Target Pair