BDBM50426474 CHEMBL1980391

SMILES COc1cc2c(cc1F)C(c1ccccc1Cl)=Nc1c(C)n[nH]c1N2

InChI Key InChIKey=UOVCGJXDGOGOCZ-UHFFFAOYSA-N

Data  1 KI  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50426474   

TargetSerine/threonine-protein kinase PLK4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426474BDBM50426474(CHEMBL1980391)
Affinity DataIC50: 7nMAssay Description:Inhibition of PLK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426474BDBM50426474(CHEMBL1980391)
Affinity DataIC50: 10nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426474BDBM50426474(CHEMBL1980391)
Affinity DataIC50: 10nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426474BDBM50426474(CHEMBL1980391)
Affinity DataKi:  11nMAssay Description:Inhibition of human PLK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426474BDBM50426474(CHEMBL1980391)
Affinity DataIC50: 24nMAssay Description:Inhibition of CHK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426474BDBM50426474(CHEMBL1980391)
Affinity DataIC50: 24nMAssay Description:Inhibition of CHK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426474BDBM50426474(CHEMBL1980391)
Affinity DataIC50: 28nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426474BDBM50426474(CHEMBL1980391)
Affinity DataIC50: 58nMAssay Description:Inhibition of aurora-A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426474BDBM50426474(CHEMBL1980391)
Affinity DataIC50: 58nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426474BDBM50426474(CHEMBL1980391)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426474BDBM50426474(CHEMBL1980391)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed