BDBM50429907 CHEMBL2333397

SMILES NS(=O)(=O)c1c(F)c(F)c(NC23CC4CC(CC(C4)C2)C3)c(F)c1F

InChI Key InChIKey=JWHCFABOVLDALW-UHFFFAOYSA-N

Data  5 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50429907   

TargetCarbonic anhydrase 13(Homo sapiens (Human))
Vilnius University Institute Of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50429907(CHEMBL2333397)
Affinity DataKd:  0.5nMpH: 7.0Assay Description:Binding affinity to human recombinant CA13 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Vilnius University Institute Of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50429907(CHEMBL2333397)
Affinity DataKd:  17nMpH: 7.0Assay Description:Binding affinity to human recombinant CA12 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Vilnius University Institute Of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50429907(CHEMBL2333397)
Affinity DataKd:  0.0500nMpH: 7.0Assay Description:Binding affinity to human recombinant CA1 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Vilnius University Institute Of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50429907(CHEMBL2333397)
Affinity DataKd:  5nMpH: 7.0Assay Description:Binding affinity to human recombinant CA2 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Vilnius University Institute Of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50429907(CHEMBL2333397)
Affinity DataKd:  1nMpH: 7.0Assay Description:Binding affinity to human recombinant CA7 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed