BDBM50431393 CHEMBL2348850

SMILES COc1cc(cc(OC)c1OC)-c1cnc2[nH]cc(C(=O)NC(C)C)c2n1

InChI Key InChIKey=WWUBOSRORWJGRU-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50431393   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50431393(CHEMBL2348850)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant truncated SYK (360 to 365 amino acid residues) using N-terminally biotinylated EPEGDYEEVLE peptide as substrate asses...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50431393(CHEMBL2348850)
Affinity DataIC50:  7.09E+3nMAssay Description:Inhibition of SYK in human whole bloodMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50431393(CHEMBL2348850)
Affinity DataIC50:  190nMAssay Description:Inhibition of SYK in human Ramos cellsMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50431393(CHEMBL2348850)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed