BDBM50433029 CHEMBL2376092

SMILES Cc1nc(N)nc2c1cc(-c1cn[nH]c1)c(=O)n2[C@H]1CC[C@@H](OCO)CC1

InChI Key InChIKey=FWRJSVJUWJBVFB-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50433029   

TargetSerine/threonine-protein kinase mTOR(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50433029BDBM50433029(CHEMBL2376092)
Affinity DataKi:  7.5nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50433029BDBM50433029(CHEMBL2376092)
Affinity DataIC50: 11nMAssay Description:Inhibition of AKT phosphorylation at Ser 473 in human BT20 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50433029BDBM50433029(CHEMBL2376092)
Affinity DataKi:  14nMAssay Description:Inhibition of mouse PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed