BDBM50433049 CHEMBL2375365

SMILES COc1ncc(-c2cc3c(C)nc(N)nc3n([C@H]3CC[C@H](OCO)CC3)c2=O)cn1

InChI Key InChIKey=PCBMOVJBHYZWMB-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50433049   

LigandChemical structure of BindingDB Monomer ID 50433049BDBM50433049(CHEMBL2375365)
Affinity DataKi:  1nMAssay Description:Inhibition of mouse PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50433049BDBM50433049(CHEMBL2375365)
Affinity DataKi:  5.10nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50433049BDBM50433049(CHEMBL2375365)
Affinity DataIC50: 22nMAssay Description:Inhibition of AKT phosphorylation at Ser 473 in human BT20 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed