BDBM50435973 CHEMBL2391866

SMILES CCCCN1C(=O)C(=O)c2cc(ccc12)S(=O)(=O)N1C[C@H](F)C[C@H]1COC

InChI Key InChIKey=LENVLTQYSOQOPN-OLZOCXBDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50435973   

TargetCaspase-3(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50435973(CHEMBL2391866)
Affinity DataIC50:  795nMAssay Description:Inhibition of human recombinant caspase-3 using Ac-DEVD-AMC as substrate assessed as accumulation of AMC preincubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50435973(CHEMBL2391866)
Affinity DataIC50:  1.88E+3nMAssay Description:Inhibition of human recombinant caspase-7 using Ac-DEVD-AMC as substrate assessed as accumulation of AMC preincubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed