BDBM50438132 CHEMBL2409865

SMILES OC[C@H]1C[C@@H](O)CCN1CCc1ccc(Nc2nc(cs2)-c2ccc(Cl)c(Cl)c2)cc1

InChI Key InChIKey=SQJKFWCRPARYPY-MOPGFXCFSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50438132   

TargetSphingosine kinase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50438132(CHEMBL2409865)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of purified human SphK2 assessed as inhibition of formation of [33P]-S1P after 50 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50438132(CHEMBL2409865)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human SPHK2 by biochemical assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50438132(CHEMBL2409865)
Affinity DataIC50:  20nMAssay Description:Inhibition of human SPHK1 by biochemical assayMore data for this Ligand-Target Pair
TargetSphingosine kinase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50438132(CHEMBL2409865)
Affinity DataIC50:  20nMAssay Description:Inhibition of purified human SphK1 assessed as inhibition of formation of [33P]-S1P after 50 mins by scintillation countingMore data for this Ligand-Target Pair