BDBM50441217 CHEMBL2431024

SMILES COc1ccc(cc1)-c1cc(Br)cc(COc2ccc(cc2)S(=O)(=O)NCC(=O)NO)c1

InChI Key InChIKey=HPKAGMQWGBOAOT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50441217   

LigandPNGBDBM50441217(CHEMBL2431024)
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
UniversitÀ

Curated by ChEMBL
LigandPNGBDBM50441217(CHEMBL2431024)
Affinity DataIC50: 1.70E+5nMAssay Description:Inhibition of recombinant human MMP-14 catalytic domain using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 4 hrs measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed