BDBM50443156 CHEMBL3085971::US8674100, 143

SMILES CC(=O)N1CCN(CC(C)(C)c2ccc(NC(=O)c3ncc(C#N)[nH]3)c(C3=CCC(C)(C)CC3)c2)CC1

InChI Key InChIKey=DALZRKQIMZJIKH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50443156   

TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50443156BDBM50443156(CHEMBL3085971 | US8674100, 143)
Affinity DataIC50: 5.70nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2014
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443156BDBM50443156(CHEMBL3085971 | US8674100, 143)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of FMS (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50443156BDBM50443156(CHEMBL3085971 | US8674100, 143)
Affinity DataIC50: 29nMAssay Description:Inhibition of FMS in mouse BMDM cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed