BDBM50444058 CHEMBL3092769::US9649309, Compound UNC2996A

SMILES CCCCNc1ncc(c(NCCCCO)n1)-c1ccccn1

InChI Key InChIKey=KKAICBOHJLVDCE-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50444058   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 50444058BDBM50444058(CHEMBL3092769 | US9649309, Compound UNC2996A)
Affinity DataIC50: 547nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 50444058BDBM50444058(CHEMBL3092769 | US9649309, Compound UNC2996A)
Affinity DataIC50: 550nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 50444058BDBM50444058(CHEMBL3092769 | US9649309, Compound UNC2996A)
Affinity DataIC50: 598nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 50444058BDBM50444058(CHEMBL3092769 | US9649309, Compound UNC2996A)
Affinity DataIC50: 600nMAssay Description:Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50444058BDBM50444058(CHEMBL3092769 | US9649309, Compound UNC2996A)
Affinity DataIC50: 4.06E+3nMAssay Description:Inhibition of Tyro-3 kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetGrowth arrest-specific protein 6(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 50444058BDBM50444058(CHEMBL3092769 | US9649309, Compound UNC2996A)
Affinity DataIC50: 4.07E+3nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetTyrosine-protein kinase receptor TYRO3(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50444058BDBM50444058(CHEMBL3092769 | US9649309, Compound UNC2996A)
Affinity DataIC50: 1.92E+4nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50444058BDBM50444058(CHEMBL3092769 | US9649309, Compound UNC2996A)
Affinity DataIC50: 2.08E+4nMAssay Description:Inhibition of Axl kinase (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed