BDBM50446479 CHEMBL3110015::US9765054, Compound 50A

SMILES ONC(=O)[C@@H]1[C@@H]([C@H]1c1ccc(cc1)-c1ncc(F)cn1)c1ccccc1

InChI Key InChIKey=QHCRWOYXPXJUJS-KZNAEPCWSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50446479   

TargetHistone deacetylase 4(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM50446479(CHEMBL3110015 | US9765054, Compound 50A)
Affinity DataIC50:  60nMAssay Description:5 μl of each solution of 1:20 diluted compound from above is transferred to a clear bottomed, black, 384-well assay plate using the Bravo or the...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446479(CHEMBL3110015 | US9765054, Compound 50A)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of human recombinant full length HDAC3-NCoR2 using Lys_Ac_AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed