BDBM50462294 CHEMBL4237453

SMILES O[C@@H](CNCCc1ccc(NC(=O)c2ccccc2)cc1)COc1cccc2[nH]ccc12

InChI Key InChIKey=HAKAXIVHVVRKQD-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50462294   

TargetBeta-3 adrenergic receptor(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50462294(CHEMBL4237453)
Affinity DataEC50:  1.40nMAssay Description:Antagonist activity at human beta3 adrenergic receptor expressed in HEK293 cells co-expressing Galpha16 assessed as inhibition of isoproterenol-induc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50462294(CHEMBL4237453)
Affinity DataEC50:  36nMAssay Description:Antagonist activity at human beta1 adrenergic receptor expressed in HEK293 cells co-expressing Galpha16 assessed as inhibition of isoproterenol-induc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50462294(CHEMBL4237453)
Affinity DataEC50:  118nMAssay Description:Antagonist activity at human beta2 adrenergic receptor expressed in HEK293 cells co-expressing Galpha16 assessed as inhibition of isoproterenol-induc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed