BDBM50463732 CHEMBL4241920

SMILES NC(=O)c1ccc(nc1Oc1ccc(Oc2ccccc2)cc1)N1CC[C@@H](C1)NC(=O)C=C

InChI Key InChIKey=VMINNJIVIPLCSD-KRWDZBQOSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50463732   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL

LigandBDBM50463732(CHEMBL4241920)Copy SMILESCopy InChI

Affinity DataIC50:  25nMAssay Description:Inhibition of human full length BTK using FITC-AHA-EEPLYWSFPAKKK-NH2 as substrate after 90 mins by microfluid mobility shift assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI