BDBM50464575 CHEMBL4282375

SMILES Cn1nc(cc1Cc1cncc(O)c1)-c1ccccc1

InChI Key InChIKey=GGCDWSJYRSGYOJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50464575   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50464575(CHEMBL4282375)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cell lysate using [1,2-3H]-cortisone as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50464575(CHEMBL4282375)
Affinity DataIC50:  17nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]-11-deoxycorticosterone as substrate after 6 hrs by HPTLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed