BDBM50464986 CHEMBL4278211

SMILES COc1ccc(cc1C(=O)Nc1cccc(n1)-c1nncn1C(C)C)S(N)(=O)=O

InChI Key InChIKey=SWXPUZFQTICUQC-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50464986   

TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50464986(CHEMBL4278211)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of recombinant full length human GST-tagged ASK1 expressed in baculovirus expression system using STK3 peptide substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50464986(CHEMBL4278211)
Affinity DataIC50:  736nMAssay Description:Inhibition of recombinant full length human ASK1 expressed in HEK293/AP1-Luc cells assessed as reduction in p38 phosphorylation after 18 hrs by HTRF ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB