BDBM50466828 CHEMBL4279192
SMILES CN(C)[C@H]1CC[C@@H](CC1)Nc1ncnc2[nH]cc([C@H]3CC[C@@H](CC3)C(N)=O)c12
InChI Key InChIKey=APLFXDJBXZUPOM-BIAGXBKMSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50466828
Affinity DataIC50: 758nMAssay Description:Inhibition of IRAK4 in human KARPAS299 cells assessed as reduction in IL-1 stimulated IRAK4 phosphorylation at Thr345/Ser346 residues preincubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant full length His-tagged human IRAK4 expressed in baculovirus expression system using 5-FAM-IPTSPITTTYFFFKKK-COOH as substrat...More data for this Ligand-Target Pair