BDBM50467339 CHEMBL4283385

SMILES NS(=O)(=O)c1ccc(CCNc2cc(Nc3ccc(\C=C\C#N)cc3)nc(Nc3ccc(cc3)C#N)n2)cc1

InChI Key InChIKey=JWUJMHRBPQBCSY-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50467339   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50467339(CHEMBL4283385)
Affinity DataEC50:  16nMAssay Description:Inhibition of wild-type HIV1 3B reverse transcriptase infected in human MT4 cells harboring GFP by scanning microscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50467339(CHEMBL4283385)
Affinity DataEC50:  91nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant infected in human MT4 cells harboring GFP by scanning microscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50467339(CHEMBL4283385)
Affinity DataEC50:  98nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant infected in human MT4 cells harboring GFP by scanning microscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50467339(CHEMBL4283385)
Affinity DataEC50:  389nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant infected in human MT4 cells harboring GFP by scanning microscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed