BDBM50467340 CHEMBL2418590

SMILES Cc1cc(C)c(Nc2cc(OCCCN3CCOCC3)nc(Nc3ccc(cc3)C#N)n2)c(C)c1

InChI Key InChIKey=VGQOQVGHPBIOJM-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50467340   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50467340(CHEMBL2418590)
Affinity DataEC50:  8.60nMAssay Description:Inhibition of HIV1 3B reverse transcriptase infected in human MT2 cells assessed as protection against virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50467340(CHEMBL2418590)
Affinity DataEC50:  38nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant infected in human MT2 cells assessed as protection against virus-induced cytopathi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50467340(CHEMBL2418590)
Affinity DataEC50:  480nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant infected in human MT2 cells assessed as protection against virus-induced cytopathic effect by M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed