BDBM50479267 Alternariol::CHEBI:64983

SMILES Cc1cc(O)cc2oc(=O)c3c(O)cc(O)cc3c12

InChI Key InChIKey=CEBXXEKPIIDJHL-UHFFFAOYSA-N

Data  28 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 28 hits for monomerid = 50479267   

TargetAurora kinase B(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  3.87E+3nMAssay Description:Inhibition of recombinant Aurora B phosphorylation in human HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50: >3.87E+4nMAssay Description:Inhibition of recombinant EPHB4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  1.31E+4nMAssay Description:Inhibition of recombinant IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of recombinant SRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  1.66E+3nMAssay Description:Inhibition of recombinant FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  8.13E+3nMAssay Description:Inhibition of recombinant INSRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  2.09E+4nMAssay Description:Inhibition of recombinant METMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  2.67E+4nMAssay Description:Inhibition of recombinant PLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  7.74E+3nMAssay Description:Inhibition of recombinant CK2alpha1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  3.71E+3nMAssay Description:Inhibition of recombinant SAKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  9.29E+3nMAssay Description:Inhibition of recombinant CDK4/CycD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  3.64E+4nMAssay Description:Inhibition of recombinant ERBB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50: >3.87E+4nMAssay Description:Inhibition of recombinant AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  3.67E+3nMAssay Description:Inhibition of recombinant ARK5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  6.19E+3nMAssay Description:Inhibition of recombinant B-RAF-V600E mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  2.12E+4nMAssay Description:Inhibition of recombinant EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  2.71E+4nMAssay Description:Inhibition of recombinant TIE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  2.82E+3nMAssay Description:Inhibition of recombinant Aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  5.03E+3nMAssay Description:Inhibition of recombinant VEGFR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  3.44E+3nMAssay Description:Inhibition of recombinant PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  9.29E+3nMAssay Description:Inhibition of recombinant FAKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  3.87E+3nMAssay Description:Inhibition of recombinant VEGFR2 phosphorylation in human HUE cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of recombinant Aurora BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  3.09E+4nMAssay Description:Inhibition of recombinant COTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  3.56E+3nMAssay Description:Inhibition of recombinant VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  3.87E+3nMAssay Description:Inhibition of recombinant IGF1R phosphorylation transfected in mouse embryonic fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  1.27E+4nMAssay Description:Inhibition of recombinant CDK2/CycAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(Alternariol | CHEBI:64983)
Affinity DataIC50:  3.87E+3nMAssay Description:Inhibition of recombinant FLT3 phosphorylation transfected in mouse embryonic fibroblastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed