BDBM50486055 CHEMBL2204507
SMILES COc1cccc(C(=O)NC2CC3CCC(C2)N3c2ccc(cn2)C(=O)NCc2ccccc2)c1C
InChI Key InChIKey=JXXRMCOYDPMQEY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50486055
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Hsp90 in human A549 cells assessed as Raf1 degradation after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 479nMAssay Description:Inhibition of His6-tagged N-terminal human HSP90alpha expressed in Escherichia coli BL21 Lys cells preincubated for 10 mins followed by SA-APC and bi...More data for this Ligand-Target Pair
Affinity DataIC50: 479nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair