BDBM50486058 CHEMBL2204517

SMILES Cc1cc(C(=O)NC2CC3CCC(C2)N3c2ccc(cn2)C(=O)NCc2ccccc2)c(C)cc1C(N)=O

InChI Key InChIKey=CHQGBLRVADDSPY-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50486058   

TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50486058(CHEMBL2204517)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Hsp90 in human A549 cells assessed as Raf1 degradation after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50486058(CHEMBL2204517)
Affinity DataIC50:  81nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB