BDBM50491230 CHEMBL2380458
SMILES COc1ccc(cc1)C1(CCC(N)=N1)c1cccc(c1)-c1cncnc1
InChI Key InChIKey=MLDNPVIFXVSEGX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50491230
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of human BACE1 (1-460) using CEVNLDAEFK as substrate preincubated for 10 mins prior to substrate addition measured after 15 mins by TR-FRE...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of BACE1-mediated soluble APPbeta release in human SH-SY5Y cells after 16 hrsMore data for this Ligand-Target Pair