BDBM50496952 CHEMBL3236466

SMILES CCCS(=O)(=O)Nc1ccc(F)c(N(C)c2ccc3ncn(C)c(=O)c3c2)c1F

InChI Key InChIKey=WWMXFNLVPRQJSD-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50496952   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50496952(CHEMBL3236466)
Affinity DataIC50:  62nMAssay Description:Inhibition of B-Raf V600E mutant in human Malme-3M cells assessed as basal ERK phosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50496952(CHEMBL3236466)
Affinity DataIC50:  11nMAssay Description:Inhibition of full-length B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB