BDBM50508889 CHEMBL4438334::US11203601, Compound Table 1.18

SMILES CC[C@@]1(c2c[nH]nc2NC2=C1C(=O)CC(C)(C)C2)c1ccccc1

InChI Key InChIKey=NCKLQXXBRWCYMA-FQEVSTJZSA-N

Data  4 IC50

PDB links: 4 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50508889   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50508889(CHEMBL4438334 | US11203601, Compound Table 1.18)
Affinity DataIC50:  515nMAssay Description:Inhibition of human GSK-3beta by mobility shift micro-fluidic assayMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50508889(CHEMBL4438334 | US11203601, Compound Table 1.18)
Affinity DataIC50:  507nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50508889(CHEMBL4438334 | US11203601, Compound Table 1.18)
Affinity DataIC50:  66nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM50508889(CHEMBL4438334 | US11203601, Compound Table 1.18)
Affinity DataIC50:  66nMAssay Description:Inhibition of human GSK-3alpha by mobility shift micro-fluidic assayMore data for this Ligand-Target Pair