BDBM50512088 CHEMBL4562491

SMILES ONC(=O)CCCCCCn1cc(Nc2ncc(Cl)c(n2)N2CCCCC2)cn1

InChI Key InChIKey=RJJTZYSKIBYNSU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50512088   

TargetHistone deacetylase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50512088(CHEMBL4562491)
Affinity DataIC50:  40nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50512088(CHEMBL4562491)
Affinity DataIC50:  60nMAssay Description:Inhibition of recombinant human TYK2 using Ulight-CAGAGAIETDKEYYTVKD as substrate measured after 60 mins by LANCE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50512088(CHEMBL4562491)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of recombinant human JAK3 using Ulight-CAGAGAIETDKEYYTVKD as substrate measured after 60 mins by LANCE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50512088(CHEMBL4562491)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant human JAK1 using Ulight-CAGAGAIETDKEYYTVKD as substrate measured after 60 mins by LANCE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50512088(CHEMBL4562491)
Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant human JAK2 using Ulight-CAGAGAIETDKEYYTVKD as substrate measured after 60 mins by LANCE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed