BDBM50547758 CHEMBL4758276

SMILES COc1ccccc1C(=O)N1CCC[C@@H](C1)c1ccnc2ncnn12

InChI Key InChIKey=BSZQESOEXLPIBQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50547758   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547758(CHEMBL4758276)
Affinity DataIC50: 912nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547758(CHEMBL4758276)
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE3B expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rat)
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547758(CHEMBL4758276)
Affinity DataIC50: 5.13E+3nMAssay Description:Inhibition of 6xHis-tagged rat recombinant PDE10A2 expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed