BDBM50568074 CHEMBL4859457

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-1=[#6](-[#8])-c2ccccc2\[#6](=[#7]\[#7]-[#6](-[#7])=S)-[#6]-1=O

InChI Key InChIKey=PINSRXIFMHJTJZ-AQTBWJFISA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50568074   

TargetCruzipain(Trypanosoma cruzi)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50568074(CHEMBL4859457)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50568074(CHEMBL4859457)
Affinity DataIC50:  6.60E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate by fluorimetric analysis relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50568074(CHEMBL4859457)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed